In the News

A 3-drug combination of elexacaftor, tezacaftor, and ivacaftor may benefit patients with cystic fibrosis with Phe508del-minimal function genotypes, in whom previous cystic fibrosis transmembrane conductance regulator (CFTR) modulator regimens have been ineffective, according to a study published in...
The US Food and Drug Administration (FDA) has approved the first triple combination therapy to treat patients aged 12 years and older with cystic fibrosis who have at least 1 F508del mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, which is estimated to represent 90...
Patients with cystic fibrosis (CF) who take ivacaftor appear to have fewer respiratory infections over time than those not taking the drug, according to a study published online in the Annals of the American Thoracic Society. The study also showed that ivacaftor may also reduce some of the most...
Adding new clinical variables to the lung allocation score can help to better identify the sickest patients with cystic fibrosis and chronic obstructive pulmonary disease (COPD) awaiting transplants, according to a study published in the American Journal of Respiratory and Critical Care Medicine...
The US Food and Drug Administration (FDA) has expanded the indication for tezacaftor/ivacaftor tablets (Symdeko) for the treatment of paediatric patients aged 6 years and older with cystic fibrosis who have certain genetic mutations. Last year, the FDA approved tezacaftor/ivacaftor to treat...

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